You're boosting a motor with an 11.5/1 compression ratio. It isn't so much fueling that is the issue in piston failures, it's the octane. You're knocking the thing to death.
E85 has (more) octane, but the LT4 fuel system can't push enough.
If you go with an additional fuel system and more PSI, it goes back to octane vs boost vs detonation until you find the weak link. Whether that be head gaskets, or pistons, who knows.
I don't know of anyone who has tried taking it that far. Usually when the first motor blows up, a buttload of money is spent upgrading everything and false theories abound as to the cause. (IMO)
Every picture of failure I have seen on the board, there is no evidence of seizing. If the piston/rings are expanding due to heat and the rings are butting, there would be scoring of the bore. All the pics show nice bores and cracked pistons.
"A hypereutectic piston is an internal combustion engine piston cast using a hypereutectic aluminum alloy with silicon content greater than the eutectic point of 12 weight percent silicon. Most aluminum-silicon casting alloys are hypoeutectic (Si content lower than the eutectic point) and contain relatively fine elemental silicon crystals formed through the eutectic reaction during solidification. In addition to fine silicon crystals, hypereutectic alloys also contain large primary silicon crystals that form before the eutectic reaction, and as a result contain a much higher phase fraction of silicon.
Consequently hypereutectic aluminum has a lower coefficient of thermal expansion, which allows engine designers to specify much tighter clearances."
https://en.wikipedia.org/wiki/Hypereutectic_piston
"The biggest drawback of adding silicon to pistons is that the piston becomes more brittle as the ratio of silicon is added.
This makes the piston more susceptible to cracking if the engine experiences pre-ignition or detonation as well as when power adders are installed."
http://www.strokerkits.com/cast-hype...orged-pistons/